RNA silencing in fungi encompasses a collection of post-transcriptional and transcriptional pathways that regulate gene expression, maintain genome integrity and defend against invasive nucleic acids.

This article is part of a series on viroids. The first, which can be read here, gave an overview of what viroids are and how they replicate. The second article described the plant host range of ...

In a recent study published in Nature Communications, a group of researchers explored how Death Induced by Survival gene Elimination (DISE) through the analysis of ribonucleic acid (RNA)-induced ...

The phenomenon was first described in 1998 by Andrew Fire and Craig Mello, who demonstrated that injecting double-stranded RNA (dsRNA) into the nematode Caenorhabditis elegans produced potent, ...

東京大学(東大)は、これまで主に細胞質(細胞核以外の部分)で起こると考えられていたmicro-RNA(miRNA)によるRNAサイレンシングにおいて、miRNAが細胞核に輸送される分子機構を解明したことを発表した。 同成果は同大大学院理学系研究科 生物化学専攻の西賢二 ...

A research team from The Hong Kong University of Science and Technology (HKUST) has made a breakthrough discovery in understanding the molecular machinery of RNA silencing. The team uncovered how the ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor miRNA; pri-miRNA, primary miRNA; RISC, ...

Gene silencing refers to any mechanism that turns down or switches off the expression of a specific gene so that less of its protein, or none at all, is produced. Crucially, the gene's DNA is left ...

A team of researchers from the Spanish National Research Council has made a significant advance in plant biotechnology by developing a new method for silencing genes. The novel technique uses ...